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The Ohio State University Comprehensive Cancer Center
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Research Programs


Innate Immunity

The central focus of this program is on basic T-cell biology, with applications in vaccine development, and on cellular innate immunity, with applications in antibody-dependent cellular cytotoxicity. The program entails three thematic subgroups: 1) T-cell recognition and cancer therapy (investigation of the basic features of T-cell immunity as it relates to the recognition and elimination of malignant cells); 2) antibody-based cancer therapy (examining factors that govern antibody production and Fc receptor signaling, and developing clinical trials derived from these studies); and 3) natural killer (NK) cell biology and clinical application (studying the development, expansion, functions and target recognition of the body’s NK cells – work that can help develop clinical strategies for enhancing antitumor activity of the innate immune system).Immunology Newsletter

Program Leaders

     

William E. Carson, III, M.D.

Professor
Surgery
N924 Doan Hall
410 W. 10th Avenue Columbus,OH. 43210

 

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(614) 292-5819

f

(614) 688-4366
william.carson@osumc.edu
 

Program Members

     

Clark L. Anderson, M.D.

Professor Emeritus
Internal Medicine
012 Heart & Lung Research Institute
473 West 12th Avenue Columbus,OH. 43210

 

o

(614) 247-7650

f

(614) 247-7669
anderson.48@osu.edu
 
     

Leona W. Ayers, M.D.

Professor
Pathology
Innovation Center - room 2046
2001 Polaris Parkway Columbus,OH. 43240

 

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(614) 293-8106

f

(614) 293-8130
ayers.1@osu.edu
 
     

Xue-feng Bai, M.D., Ph.D.

Asst Professor
Pathology
158 Hamilton
1645 Neil Ave Columbus,OH. 43210

 

o

(614) 292-8421

f

(614) 292-7072
bai.21@osu.edu
 
     

Don M Benson, M.D., Ph.D.

Asst Professor-Clinical
Internal Medicine
A445 Starling Loving Hall
320 W 10th Ave. Columbus,OH. 43210

 

o

(614) 366-3802

f

(614) 293-6690
Don.Benson@osumc.edu
 
     

Ginny L. Bumgardner, M.D., Ph.D.

Professor
Surgery
363 Means Hall
1654 Upham Dr. Columbus,OH. 43210

 

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(614) 293-6177

f

(614) 293-4541
ginny.bumgardner@osumc.edu
 
     

Jonathan P Butchar, Ph.D.

Research Scientist
Internal Medicine
455 DHLRI
473 W 12th Ave Columbus,OH. 43210

 

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(614) 292-4611

f

(614) 247-4575
jon.butchar@osumc.edu
 
     

John C. Byrd, M.D.

Professor
Internal Medicine
B302 Starling-Loving
320 W. 10th Avenue Columbus,OH. 43210

 

o

(614) 293-7509

f

(614) 293-7526
john.byrd@osumc.edu

 

Other Programs:

Experimental Therapeutics
     

Michael A. Caligiuri, M.D.

Professor
Internal Medicine/ OSUCCC
521B James Cancer Hospital
300 W. 10th Avenue Columbus,OH. 43210

 

o

(614) 293-7521

f

(614) 293-3122
michael.caligiuri@osumc.edu
     

David E. Cohn, M.D.

Assoc Professor
Obstetrics & Gynecology
M210 Starling-Loving Hall
320 W. Tenth Avenue Columbus,OH. 43210

 

o

(614) 293-8737

f

(614) 293-3078
david.cohn@osumc.edu
 
     

Joan E. Durbin, M.D., Ph.D.

Assoc Professor
Pediatrics
Children's Hospital, Wexner 411
700 Children's Drive Columbus,OH. 43205

 

o

(614) 722-2798

f

(614) 722-2817
Joan.Durbin@nationwidechildrens.org
 
     

Tim D Eubank, Ph.D.

Research Asst Professor
Internal Medicine
425 DHLRI
473 W 12th Avenue Columbus,OH. 43210

 

o

(614) 247-7652

f

(614) 688-4662
tim.eubank@osumc.edu
 
     

Emilio Flano, Ph.D.

Asst Professor
Pediatrics
Children's Research Institute
700 Children's Drive WA4015 Columbus,OH. 43205

 

o

(614) 722-4064

f

(614) 722-3680
Emilio.Flano@nationwidechildrens.org
 
     

Wendy L. Frankel, M.D.

Professor
Pathology
E421 Doan Hall
410 W 10th Ave Columbus,OH. 43210

 

o

(614) 293-8496

f

(614) 293-7626
wendy.frankel@osumc.edu
 
     

Jian-xin Gao, M.D., Ph.D.

Research Asst Professor
Pathology
146 Hamilton
1645 Neil Ave Columbus,OH. 43210

 

o

(614) 293-7237

f

(614) 293-7237
gao.49@osu.edu
 
     

Phyllis M Hammond, Ph.D.

Cl Professor
Pathology
412 Childrens Hospital
700 Childrens Dr. Columbus,OH. 43205

 

o

(614) 722-5302

f

hammond.7@osu.edu
 
     

David Jarjoura, Ph.D.

Research Professor
College of Public Health
M-410
320 W 10th Ave Columbus,OH. 43210

 

o

(614) 293-6471

f

(614) 293-6902
David.Jarjoura@osumc.edu
 
     

Scott D. Jewell, Ph.D.

Research Assc Professor
Pathology
Innovation Center Room 2060
2001 Polaris Parkway Columbus,OH. 43240

 

o

(614) 293-6906

f

scott.jewell@osumc.edu
 
     

Pravin T. Kaumaya, Ph.D.

Professor
Obstetrics & Gynecology
316 TMRF
420 W. 12th Avenue Columbus,OH. 43210

 

o

(614) 292-7028

f

(614) 292-1135
kaumaya.1@osu.edu
 
     

William P. Lafuse, Ph.D.

Professor
Molecular Virology, Immunology & Medical Genetics
2178 Graves Hall
333 W. 10th Avenue Columbus,OH. 43210

 

o

(614) 292-0652

f

(614) 292-9805
lafuse.1@osu.edu
 
     

Larry C. Lasky, M.D.

Assoc Professor
Pathology
310 Doan Hall
410 W. 10th Avenue Columbus,OH. 43210

 

o

(614) 293-3020

f

(614) 293-4591
larry.lasky@osumc.edu
 
     

L. James Lee, Ph.D.

Professor
Chemical & Biomolecular Engineering
1012 Smith Laboratory
140 W. 19th Ave Columbus,OH. 43210

 

o

(614) 292-2408

f

(614) 292-3769
Lee.31@osu.edu
 
     

Gregory B. Lesinski, Ph.D.

Asst Professor
Internal Medicine
320B Comprehensive Cancer Center/Wiseman Hall
400 W. 12th Ave. Columbus,OH. 43210

 

o

(614) 292-1551

f

(614) 688-4366
gregory.lesinski@osumc.edu
 
     

Clay B Marsh, M.D.

Professor
Internal Medicine
211 Means Hall
1654 Upham Drive Columbus,OH. 43210

 

o

(614) 293-9309

f

(614) 293-4925
clay.marsh@osumc.edu
 
     

Edward W. Martin, Jr., M.D.

Professor
Surgery
N911 Doan Hall
410 W. 10th Avenue Columbus,OH. 43210

 

o

(614) 293-8843

f

(614) 293-3465
edward.martin@osumc.edu
 
     

Susan D Moffatt-Bruce, M.D.

Asst Professor
Surgery
N-835 Doan Hall
410 W. 10th Ave. Columbus,OH. 43210

 

o

(614) 293-4509

f

Susan.Moffatt-Bruce@osumc.edu
 
     

Natarajan Muthusamy, D.V.M., Ph.D.

Research Assc Professor
Internal Medicine
455E CCC
410 W 12th Ave Columbus,OH. 43210

 

o

(614) 293-7406

f

Raj.Muthusamy@osumc.edu
 
     

Joseph S. Palumbo, M.D.

Research Asst Professor
Pediatrics
Division of Hematology/Oncology
3333 Burnet Ave Cincinnati,OH. 45229

 

o

(513) 636-4915

f

(513) 636-3549
joe.palumbo@cchmc.org
 
     

Virginia M. Sanders, Ph.D.

Professor
Molecular Virology, Immunology & Medical Genetics
2194 Graves Hall
333 West 10th Avenue Columbus,OH. 43210

 

o

(614) 292-3349

f

(614) 292-9805
sanders.302@osu.edu
 
     

Larry S. Schlesinger, M.D.

Professor
Internal Medicine
Medical Research Facility, Rm 216
420 W. 12th Ave Columbus,OH. 43210

 

o

(614) 292-8684

f

(614) 292-9616
larry.schlesinger@osumc.edu
 
     

Susheela Tridandapani, Ph.D.

Assoc Professor
Internal Medicine
405D Davis Heart & Lung Inst.
473 W. 12th Avenue Columbus,OH. 43210

 

o

(614) 247-6768

f

(614) 293-4799
Susheela.Tridandapani@osumc.edu
 
     

James R. Van Brocklyn, Ph.D.

Asst Professor
Pathology
4164 Graves Hall
333 West 10th Avenue Columbus,OH. 43210

 

o

(614) 292-7515

f

(614) 292-5849
James.vanbrocklyn@osumc.edu
 
     

Peng G. Wang, Ph.D.

Professor
Biochemistry
876 Biological Sciences Building
484 W.12th Avenue Columbus,OH. 43210

 

o

(614) 292-9884

f

(614) 688-3106
wang.892@osu.edu
 
     

Mark D. Wewers, M.D.

Professor
Internal Medicine
110 Heart & Lung Research Institute
473 West 12th Avenue Columbus,OH. 43210

 

o

(614) 293-4925

f

(614) 293-4799
mark.wewers@osumc.edu
 
     

Caroline C. Whitacre, Ph.D.

Professor
Molecular Virology, Immunology & Medical Genetics
ATTN:Peggy Link 2078 Graves Hall
333 W 10th Ave Columbus,OH. 43210

 

o

(614) 292-5889

f

(614) 292-9805
caroline.whitacre@osumc.edu